九州大学生体材料学分野

Publication list

	2025　 2024　 2023　 2022　 2021　 2020　 2019　 2018　 2017　 2016　 2015
	【2025 & In press】・Saki Takeda, Akira Tsuchiya, Masafumi Moriyama, Kunio Ishikawa 　Optimization of the structure of three-dimensional interconnected porous carbonate apatite bone grafts with spherical granules   　Dental Materials Journal, 2025. (In press) 　・Koichiro Hayashi, Tatsuya Tokumaru, Keigo Shibahara, Ahmad Nazir Taleb Alashkar, Cheng Zhang, Ryo Kishida, Yasuharu Nakashima, Kunio Ishikawa 　Wood-derived hydrogels for osteochondral defect repair   　ACS Nano, 2025. (In press) 　・Keigo Shibahara, Koichiro Hayashi, Yasuharu Nakashima, Kunio Ishikawa 　Controlling the pore size of carbonate apatite honeycomb scaffolds enhances orientation and strength of regenerated bone   　Biomaterials Advances, 166, 214026, 2025. 　doi: 10.1016/j.bioadv.2024.214026
	【2024 & In press】
	Back to top ・Saki Takeda, Akira Tsuchiya, Masafumi Moriyama, Kunio Ishikawa 　Physical and histological comparison of three-dimensional interconnected porous carbonate apatite bone graft fabricated with cylindrical and spherical granules   　Ceramics International, 50, 53544-53551, 2024. 　doi: 10.1016/j.ceramint.2024.10.203 ・Luis Miguel Torres Escalante, Koichiro Hayashi, Kunio Ishikawa 　Migration prevention of carbonate apatite granules through crystal interlocking driven by bassanite-to-gypsum transformation on granule surface   　Applied Sciences, 14, 11261, 2024. 　doi: 0.3390/app142311261 ・Koichiro Hayashi, Cheng Zhang, Ahmad Nazir Taleb Alashkar, Kunio Ishikawa 　Carbonate apatite honeycomb scaffold-based drug delivery system for repairing osteoporotic bone defects   　ACS Applied Materials & Interfaces, 16, 45956–45968, 2024. 　doi: 10.1021/acsami.4c08047 ・Koichiro Hayashi, Masaya Shimabukuro, Cheng Zhang, Ahmad Nazir Taleb Alashkar, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Silver phosphate-modified carbonate apatite honeycomb scaffolds for anti-infective and pigmentation-free bone tissue engineering   　Materials Today Bio, 27, 101161, 2024. 　doi: 10.1016/j.mtbio.2024.101161 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Hematopoietic function restoration by transplanting bone marrow niches in vivo engineered using carbonate apatite honeycomb bioreactors   　Small Structures, 2400065, 2024. 　doi: 10.1002/sstr.202400065　Selected for Inside Front Cover ・Luis Miguel Torres Escalante, Akira Tsuchiya, Lou Zhanrui, Miki Morinobu, Kunio Ishikawa 　Fabrication and histological evaluation of self-setting granular cement using calcium sulfate hemihydrate granules with different pore distribution   　Dental Materials Journal, 43, 573-581, 2024. 　doi: 10.4012/dmj.2023-248 ・Muhammad Amir Jamilludin, Koichiro Hayashi, Yusril Yusuf, Kunio Ishikawa 　Fabrication of magnesium-doped biphasic calcium phosphate granules with sea urchin spine-derived porous structure   　Ceramics International, 50, 25988-25999, 2024.　　doi: 10.1016/j.ceramint.2024.04.341 ・Ahmad Nazir Taleb Alashkar, Koichiro Hayashi, Kunio Ishikawa 　Lamellar septa-like structured carbonate apatite scaffolds with layer-by-layer fracture behavior for bone regeneration   　Biomimetics, 9, 112, 2024. 　doi: 10.3390/biomimetics9020112 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Transformable carbonate apatite chains as a novel type of bone graft   　Advanced Healthcare Materials, 13, 2303245, 2024. 　doi: 10.1002/adhm.202303245　Selected for Cover Picture ・Masaya Shimabukuro, Miki Morinobu, Akira Tsuchiya, Ryo Kishida, Masakazu Kawashita, Kunio Ishikawa 　Antibacterial and osteogenic thin film on Ti-6Al-4V surface formed by passivation process in copper hydroxide solution   　Science and Technology of Advanced Materials, 25, 2303327, 2024. 　doi: 10.1080/14686996.2024.2303327/ma16247518
	【2023】
	Back to top ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Effects of space dimensionality within scaffold for bone regeneration with large and oriented blood vessels   　Materials, 16, 7518, 2023. 　doi: 10.3390/ma16247518 ・Cheng Zhang, Koichiro Hayashi, Kunio Ishikawa 　Osseointegration enhancement by controlling dispersion state of carbonate apatite in polylactic acid implant   　Colloids and Surfaces B: Biointerfaces, 232, 113588, 2023. 　doi: 10.1016/j.colsurfb.2023.113588 ・Janice Lay Tin Tan, Masaya Shimabukuro, Mamiko Kobayashi, Ryo Kishida, Masakazu Kawashita, Kunio Ishikawa 　Ant‐nest type porous scaffold with micro‐struts consisting of carbonate apatite for promoting bone formation and scaffold resorption   　Journal of Biomedical Materials Research Part A, 112, 31-43, 2023. 　doi: 10.1002/jbm.a.37608 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Superiority of triply periodic minimal surface gyroid structure to strut-based grid structure in both strength and bone regeneration   　ACS Applied Materials & Interfaces, 15, 34570–34577, 2023. 　doi: 10.1021/acsami.3c06263 ・Keigo Shibahara, Koichiro Hayashi, Yasuharu Nakashima, Kunio Ishikawa 　Reconstruction of load-bearing segmental bone defects using carbonate apatite honeycomb blocks   　ACS Materials Au, 3, 321-336, 2023. 　doi: 10.1021/acsmaterialsau.3c00008 ・Koichiro Hayashi, Toshiki Yanagisawa, Masaya Shimabukuro, Ryo Kishida, Kunio Ishikawa 　Gear-shaped carbonate apatite granules with a hexagonal macropore for rapid bone regeneration   　Computational and Structural Biotechnology Journal, 21, 2514-2523, 2023. 　doi: 10.1016/j.csbj.2023.03.053 ・Koichiro Hayashi, Kunio Ishikawa 　Endowing osseointegration ability to bioinert alumina by carbonate apatite coating   　Surfaces and Interfaces, 36, 102617, 2023. 　doi: 10.1016/j.surfin.2022.102617 ・Janice Lay Tin Tan, Masaya Shimabukuro, Ryo Kishida, Kunio Ishikawa 　Fabrication and histological evaluation of ant-nest type porous carbonate apatite artificial bone using polyurethane foam as a porogen   　Journal of Biomedical Materials Research Part B, 111, 560-567, 2023. 　doi: 10.1002/jbm.b.35173
	【2022】
	Back to top ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Channel aperture characteristics of carbonate apatite honeycomb scaffolds affect ingrowths of bone and fibrous tissues in vertical bone augmentation   　Bioengineering, 9, 627, 2022. 　doi: 10.3390/bioengineering9110627 ・Koichiro Hayashi, Toshiki Yanagisawa, Ryo Kishida, Kunio Ishikawa 　Effects of scaffold shape on bone regeneration: tiny shape differences affect the entire system   　ACS Nano, 16, 11755-11768, 2022. 　doi: 10.1021/acsnano.2c03776 ・Koichiro Hayashi, Masaya Shimabukuro, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Structurally optimized honeycomb scaffolds with outstanding ability for vertical bone augmentation 　Journal of Advanced Research, 41, 101-112, 2022. 　doi: 10.1016/j.jare.2021.12.010 ・Keisuke Tanaka, Akira Tsuchiya, Yoichiro Ogino, Yasunori Ayukawa, Kunio Ishikawa 　Comparison of calcite and vaterite as precursors for CO3Ap artificial bone fabrication through a dissolution–precipitation reaction   　Ceramics International, 45, 26425-26431, 2022. 　doi: 10.1016/j.ceramint.2022.05.336 ・Akira Tsuchiya, Pery Freitas, Nozomi Nagashima, Kunio Ishikawa 　Influence of pH and ion components in the liquid phase on the setting reaction of carbonate apatite granules 　Dental Materials Journal, 41, 209-213, 2022. 　doi: 10.4012/dmj.2021-211 ・Tansza Setiana Putri, Sunarso, Koichiro Hayashi, Kanji Tsuru, Kunio Ishikawa 　Feasibility study on surface morphology regulation of β-tricalcium phosphate bone graft for enhancing cellular response 　Ceramics International, 48, 13395-13399, 2022. 　doi: 10.1016/j.ceramint.2022.02.200 ・Masaya Shimabukuro, Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Surface functionalization with copper endows carbonate apatite honeycomb scaffold with antibacterial, proangiogenic, and pro-osteogenic activities 　Biomaterials Advances, 135, 212751, 2022. 　doi: 10.1016/j.bioadv.2022.212751 ・Koichiro Hayashi, Toshiki Yanagisawa, Masaya Shimabukuro, Ryo Kishida, Kunio Ishikawa 　Granular honeycomb scaffolds composed of carbonate apatite for simultaneous intra- and inter-granular osteogenesis and angiogenesis   　Materials Today Bio, 14, 100247, 2022. 　doi: 10.1016/j.mtbio.2022.100247 ・Koichiro Hayashi, Akira Tsuchiya, Masaya Shimabukuro, Kunio Ishikawa 　Multiscale porous scaffolds constructed of carbonate apatite honeycomb granules for bone regeneration 　Materials & Design, 215, 110468, 2022. 　doi: 10.1016/j.matdes.2022.110468 ・Pery Freitas, Ryo Kishida, Koichiro Hayashi, Akira Tsuchiya, Masaya Shimabukuro, Kunio Ishikawa 　Fabrication and histological evaluation of porous carbonate apatite blocks using disodium hydrogen phosphate crystals as a porogen and phosphatization accelerator 　Journal of Biomedical Materials Research Part A, 110, 1278-1290, 2022. 　doi: 10.1002/jbm.a.37374 ・Keigo Shibahara, Koichiro Hayashi, Yasuharu Nakashima, Kunio Ishikawa 　Effects of channels and micropores in honeycomb scaffolds on reconstruction of segmental bone defect 　Frontiers in Bioengineering and Biotechnology, 10, 825831, 2022. 　doi: 10.3389/fbioe.2022.825831 ・Maab Elsheikh, Ryo Kishida, Koichiro Hayashi, Akira Tsuchiya, Masaya Shimabukuro, Kunio Ishikawa 　Effects of pore interconnectivity on bone regeneration in carbonate apatite blocks 　Regenerative Biomaterials, 9, rbac010, 2022. 　doi: 10.1093/rb/rbac010 ・Koichiro Hayashi, Masaya Shimabukuro, Kunio Ishikawa 　Antibacterial honeycomb scaffolds for achieving infection prevention and bone regeneration 　ACS Applied Materials & Interfaces, 14, 3762-3772, 2022. 　doi: 10.1021/acsami.1c20204 ・Masaya Shimabukuro, Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　No-observed-effect level of silver phosphate in carbonate apatite artificial bone on initial bone regeneration 　ACS Infectious Diseases, 8, 159-169, 2022. 　doi: 10.1021/acsinfecdis.1c00480 ・Kunio Ishikawa, Pery Freitas, Ryo Kishida, Koichiro Hayashi, Akira Tsuchiya 　Fabrication of vaterite blocks from a calcium hydroxide compact 　Ceramics International, 48, 4153-4157, 2022. 　doi: 10.1016/j.ceramint.2021.10.206 ・Masaya Shimabukuro, Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Effects of carbonate ions in phosphate solution on the fabrication of carbonate apatite through a dissolution–precipitation reaction 　Ceramics International, 48(1), 1032-1037, 2022. 　doi: 10.1016/j.ceramint.2021.09.188 ・Koichiro Hayashi, Kunio Ishikawa 　Honeycomb scaffolds capable of ectopic osteogenesis: Histological evaluation of osteoinduction mechanism 　Nano Select, 3, 60-77, 2022. 　doi: 10.1002/nano.202000283 ・Kaai Deguchi, Shunsuke Nomura, Akira Tsuchiya, Ichiro Takahashi, Kunio Ishikawa 　Effects of the carbonate content in carbonate apatite on bone replacement 　Journal of Tissue Engineering and Regenerative Medicine, 16, 200-206, 2022. 　doi: 10.1002/term.3270
	【2021】
	Back to top ・Kozue Yamashita, Atushi Tomokiyo, Taiga Ono, Keita Ipposhi, M. Anas Alhasan, Akira Tsuchiya, Sayuri Hamano, Hideki Sugii, Shinichi Yoshida, Tomohiro Itoyama, Hidefumi Maeda 　Mineral trioxide aggregate immersed in sodium hypochlorite reduce the osteoblastic differentiation of human periodontal ligament stem cells. 　Scientific Reports, 11, 22091, 2021. 　doi: 10.1038/s41598-021-01545-3 ・Koichiro Hayashi, Masaya Shimabukuro, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Honeycomb scaffolds capable of achieving barrier membrane-free guided bone regeneration 　Materials Advances, 2, 7638-7649, 2021. 　doi: 10.1039/D1MA00698C　Selected for Front Cover ・Koichiro Hayashi, Kunio Ishikawa 　Carbonate apatite artificial bone 　Science and Technology of Advanced Materials, 22(1), 683-694, 2021. 　doi: 10.1080/14686996.2021.1947120 ・Keigo Shibahara, Koichiro Hayashi, Yasuharu Nakashima, Kunio Ishikawa 　Honeycomb scaffold-guided bone reconstruction of critical-sized defects in rabbit ulnar shafts 　ACS Applied Bio Materials, 4, 6821-6831, 2021. 　doi: 10.1021/acsabm.1c00533 ・Cheng Zhang, Koichiro Hayashi, Kunio Ishikawa 　Enhancement of bone to polylactic acid plate bonding by carbonate apatite coating 　Ceramics International, 47(20), 28348-28356, 2021. 　doi: 10.1016/j.ceramint.2021.06.252 ・Ryo Kishida, Maab Elsheikh, Koichiro Hayashi, Akira Tsuchiya, Kunio Ishikawa 　Fabrication of highly interconnected porous carbonate apatite blocks based on the setting reaction of calcium sulfate hemihydrate granules 　Ceramics International, 47, 19856-19863, 2021. 　doi: 10.1016/j.ceramint.2021.03.324 ・Koichiro Hayashi, Nao Kato, Masaki Kato, Kunio Ishikawa 　Impacts of channel direction on bone tissue engineering in 3D-printed carbonate apatite scaffolds 　Materials & Design, 204, 109686, 2021. 　doi: 10.1016/j.matdes.2021.109686 ・Taiga Ono, Atsushi Tomokiyo, Keita Ipposhi, Kozue Yamashita, M Anas Alhasan, Yudai Miyazaki, Yoshihiro Kunitomi, Akira Tsuchiya, Kunio Ishikawa, Hidefumi Maeda 　Generation of biohybrid implants using a multipotent human periodontal ligament cell line and bioactive core materials 　Journal of Cellular Physiology, 236(9), 6742-6753, 2021. 　doi: 10.1002/jcp.30336 ・Yuta Sakemi, Koichiro Hayashi, Akira Tsuchiya, Yasuharu Nakashima, Kunio Ishikawa 　Reconstruction of critical-size segmental defects in rat femurs using carbonate apatite honeycomb scaffolds 　Journal of Biomedical Materials Research Part A, 109(9), 1613-1622, 2021. 　doi: 10.1002/jbm.a.37157 ・Koichiro Hayashi, Kunio Ishikawa 　Honeycomb scaffolds fabricated using extrusion molding and sphere packing theory for bone regeneration 　ACS Applied Bio Materials, 4, 721-730, 2021. 　doi: 10.1021/acsabm.0c01279
	【2020】
	Back to top ・Kunio Ishikawa, Edita Garskaite, Aivaras Kareiva 　Sol–gel synthesis of calcium phosphate-based biomaterials — A review of environmentally benign, simple, and effective synthesis routes 　Journal of Sol-Gel Science, 94, 551-572, 2020. 　doi: 10.1007/s10971-020-05245-8 ・Thet Thet Swe, Khairul Anuar Shariff, Hasmaliza Mohamad, Kunio Ishikawa, Koichiro Hayashi, Mohamad Hafizi Abu Bakar 　Behavioural response of cells and bacteria on single and multiple doped Sr and Ag S53P4 Sol-Gel Bioglass 　Ceramics International, 46, 17881-17890, 2020. 　doi: 10.1016/j.ceramint.2020.04.094 ・Keisuke Tanaka, Akira Tsuchiya, Yoichiro Ogino, Kiyoshi Koyano, Kunio Ishikawa 　Fabrication and histological evaluation of a fully interconnected porous CO₃Ap block formed by hydrate expansion of CaO granules. 　ACS Applied Bio Materials, 3, 8872-8878, 2020. 　doi: 10.1021/acsabm.0c01176 ・Michihiro Nakamura, Koichiro Hayashi, Junna Nakamura, Chihiro Mochizuki, Takuya Murakami, Hirokazu Miki, Shuji Ozaki, Masahiro Abe 　Near-infrared fluorescent thiol-organosilica nanoparticles that are functionalized with IR-820 and their applications for long-term imaging of in situ labeled cells and depth-dependent tumor in vivo imaging 　Chemistry of Materials, 32, 7201-7214, 2020. 　doi: 10.1021/acs.chemmater.0c01414 ・Koichiro Hayashi, Atsuto Tokuda, Jin Nakamura, Ayae Sugawara-Narutaki, Chikara Ohtsuki 　Tearable and fillable composite sponges capable of heat generation and drug release in response to alternating magnetic field 　Materials, 13(16), 3637, 2020. 　doi: 10.3390/ma13163637 ・Koichiro Hayashi, Kunio Ishikawa 　Effects of nanopores on the mechanical strength, osteoclastogenesis, and osteogenesis in honeycomb scaffolds. 　Journal of Materials Chemistry B (Selected as a HOT Paper.)* 8, 8536, 2020.* 　doi: 10.1039/D0TB01498B ・Rui Shi, Koichiro Hayashi, Kunio Ishikawa 　Rapid osseointegration bestowed by carbonate apatite coating of rough titanium 　Advanced Materials Interfaces, 7, 2000636, 2020. 　doi: 10.1002/admi.202000636. ・Tansza Permata Setiana Putri, Koichiro Hayashi, Kunio Ishikawa 　Fabrication of three-dimensional interconnected porous blocks composed of robust carbonate apatite frameworks 　Ceramics International, 46, 20045-20049, 2020. 　doi: 10.1016/j.ceramint.2020.05.076 ・Rui Shi, Koichiro Hayashi, Le Thi Bang, Kunio Ishikawa 　Effects of surface roughening and calcite coating of titanium on cell growth and differentiation 　Journal of Biomaterials Applications, 34, 917-927, 2020. 　doi: 10.1177/0885328219883765 ・Sunarso, Akira Tsuchiya, Riki Toita, Kanji Tsuru, Kunio Ishikawa 　Enhanced osseointegration capability of poly(ether ether ketone) via combined phosphate and calcium surface-functionalization 　International Journal of Molecular Sciences, 21, 198, 2020. 　doi: 10.3390/ijms21010198s ・Le Thi Bang, Rui Shi, Bui Duc Long, S. Ramesh, Shi Xingling, Yuki Sugiura, Kunio Ishikawa 　Biological responses of MC3T3-E1 on calcium carbonate coatings fabricated by hydrothermal reaction on titanium 　Biomedical Materials, 15(3), 035004, 2020. 　doi: 10.1088/1748-605X/ab6939 ・Stasys Tautkus, Kunio Ishikawa, Rimantas Ramanauskas, Aivaras Kareiva 　Zinc and chromium co-doped calcium hydroxyapatite: Sol-gel synthesis, characterization, behaviour in simulated body fluid and phase transformations 　Journal of Solid State Chemistry, 284, 121202, 2020. 　doi: 10.1016/j.jssc.2020.121202 ・Inga Grigoraviciute-Puroniene, Zivile Stankeviciute, Kunio Ishikawa, Aivaras Kareiva 　Formation of calcium hydroxyapatite with high concentration of homogeneously distributed silver 　Microporous and Mesoporous Materials, 293, 109806, 2020. 　doi: 10.1016/j.micromeso.2019.109806 ・Koichiro Hayashi, Melvin L. Munar, Kunio Ishikawa 　Effects of macropore size in carbonate apatite honeycomb scaffolds on bone regeneration 　Materials Science and Engineering: C, 111, 110848, 2020. 　doi: 10.1016/j.msec.2020.110848 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Granular honeycombs composed of carbonate apatite, hydroxyapatite, and β-tricalcium phosphate as bone graft substitutes: Effects of composition on bone formation and maturation 　ACS Applied Bio Materials, 3, 1787-1795, 2020. 　doi: 10.1021/acsabm.0c00060 ・Naoyuki Fukuda, Kunio Ishikawa, Kazuya Akita, Naito Kurio, Yoshihide Mori, Youji Miyamoto 　Effects of acidic calcium phosphate concentration on setting reaction and tissue response to β-tricalcium phosphate granular cement 　Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 108, 22-29, 2020. 　doi: 10.1002/jbm.b.34361 ・Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Keiko Kudoh, Naito Kurio, Kanji Tsuru, Kunio Ishikawa, Youji Miyamoto 　Fabrication of porous carbonate apatite granules using microfiber and its histological evaluations in rabbit calvarial bone defects 　Journal of Biomedical Materials Research: Part A, 108, 709-721, 2020. 　doi: 10.1002/jbm.a.36850 ・Olga Opuchovic, Mindaugas Andrulevicius, Sigitas Tamulevicius, Jean-Luc Rehspringer, Aldona Beganskiene, Ramunas Skaudzius, Kunio Ishikawa, Aivaras Kareiva 　Cerium doping and cerium aluminium co-doping effects on the sol-gel processing of Y₃Fe₅O₁₂ (YIG): Bulk and thin films 　Solid State Sciences, 99, 106065, 2020. 　doi: 10.1016/j.solidstatesciences.2019.106065 ・Sunarso, Riki Toita, Kanji Tsuru, Kunio Ishikawa 　Ozone-gas-mediated surface hydrophilization enhances the cell responses to titanium 　Materials Letters, 261, 127168, 2020. 　doi: 10.1016/j.matlet.2019.127168 ・Takamitsu Mano, Kazuya Akita, Naoyuki Fukuda, Kumiko Kamada, Naito Kurio, Kunio Ishikawa, Youji Miyamoto 　Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation 　Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 108, 1450-1459, 2020. 　doi: 10.1002/jbm.b.34492
	【2019】
	Back to top ・Yuta Sakemi, Koichiro Hayashi, Akira Tsuchiya, Yasuharu Nakashima, Kunio Ishikawa 　Fabrication and histological evaluation of porous carbonate apatite block from gypsum block containing spherical phenol resin as a porogen 　Materials, 12, 3997, 2019. 　doi: 10.3390/ma12233997 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Honeycomb blocks composed of carbonate apatite, β-tricalcium phosphate, and hydroxyapatite for bone regeneration: effects of composition on biological responses 　Materials Today Bio, 4, 100031, 2019. 　doi: 10.1016/j.mtbio.2019.100031 ・Koichiro Hayashi, Ryo Kishida, Akira Tsuchiya, Kunio Ishikawa 　Carbonate apatite micro-honeycombed blocks generate bone marrow-like tissues as well as bone. 　Advanced Biosystems, 3, 1900140, 2019. 　doi: 10.1002/adbi.201900140 ・Yukari Ihara, Toru Takeshita, Shinya Kageyama, Rie Matsumi, Mikari Asakawa, Yukie Shibata, Yuki Sugiura, Kunio Ishikawa, Ichiro Takahashi, Yoshihisa Yamashita 　Identification of initial colonizing bacteria in dental plaques from young adults using full-length 16S rRNA gene sequencing 　American Society for Microbiology Journals, 4(5), e00360-19, 2019. 　doi: 10.1128/mSystems.00360-19 ・Kunio Ishikawa 　Carbonate apatite bone replacement: learn from the bone 　Journal of the Ceramic Society of Japan, 127(9), 595-601, 2019. 　doi: 10.2109/jcersj2.19042 ・Garima Tripathi, Kunio Ishikawa 　Fabrication and in vitro dissolution evaluation of low-crystalline beta-TCP blocks through aqueous solution mediated phase conversion 　Materials Science and Engineering: C, 101, 228-231, 2019. 　doi: 10.1016/j.msec.2019.03.106 ・Inga Grigoraviciute-Puroniene, Yuhei Tanaka, Visata Vegelyte, Yuko Nishimoto, Kunio Ishikawa, Aivaras Kareiva 　A novel synthetic approach to low-crystallinity calcium deficient hydroxyapatite 　Ceramics International, 45(12), 15620-15623, 2019. 　doi: 10.1016/j.ceramint.2019.05.072 ・Inga Grigoraviciute-Puroniene, Aleksej Zarkov, Kanji Tsuru, Kunio Ishikawa, Aivaras Kareiva 　A novel synthetic approach for the calcium hydroxyapatite from the food products 　Journal of Sol-Gel Science and Technology, 91(1), 63-71, 2019. 　doi: 10.1007/s10971-019-05020-4 ・Lauryna Sinusaite, Inga Grigoraviciute-Puroniene, Anton Popov, Kunio Ishikawa, Aivaras Kareiva, Aleksej Zarkov 　Controllable synthesis of tricalcium phosphate (TCP) polymorphs by wet precipitation: Effect of washing procedure 　Ceramics International, 45(9), 12423-12428, 2019. 　doi: 10.1016/j.ceramint.2019.03.174 ・Vilma Jonauske, Sandra Stanionyte, Shih-Wen Chen, Aleksej Zarkov, Remigijus Juskenas, Algirdas Selskis, Tadas Matijosius, Thomas C.K. Yang, Kunio Ishikawa, Rimantas Ramanauskas, Aivaras Kareiva 　Characterization of sol-gel derived calcium hydroxyapatite coatings fabricated on patterned rough stainless steel surface 　Coatings, 9(5), 334, 2019. 　doi: 10.3390/coatings9050334 ・Koichiro Hayashi, Melvin L. Munar, Kunio Ishikawa 　Carbonate apatite granules with uniformly sized pores that arrange regularly and penetrate straight through granules in one direction for bone regeneration 　Ceramics International, 45, 15429–15434, 2019. 　doi: 10.1016/j.ceramint.2019.05.042 ・Kunio Ishikawa, Tya Indah Arifta, Koichiro Hayashi, Kanji Tsuru 　Fabrication and evaluation of interconnected porous carbonate apatite from alpha tricalcium phosphate spheres 　Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 107(2), 269-277, 2019. 　doi: 10.1002/jbm.b.34117 ・Naoyuki Fukuda, Akira Tsuchiya, Sunarso, Riki Toita, Kanji Tsuru, Yoshihide Mori, Kunio Ishikawa 　Surface plasma treatment and phosphorylation enhance the biological performance of poly(ether ether ketone) 　Colloids and Surfaces B: Biointerfaces, 197, 36-42, 2019. 　doi: 10.1016/j.colsurfb.2018.09.032 ・Yuki Sugiura, Kunio Ishikawa 　Fabrication of pure octacalcium phosphate blocks from dicalcium hydrogen phosphate dihydrate blocks via a dissolution-precipitation reaction in a basic solution 　Materials Letters, 293, 143-146, 2019. 　doi: 10.1016/j.matlet.2018.12.093 ・Kunio Ishikawa, Melvin L. Munar, Kanji Tsuru, Youji Miyamoto 　Fabrication of carbonate apatite honeycomb and its tissue response 　Journal of Biomedical Materials Research: Part A, 107A, 1014-1020, 2019. 　doi: 10.1002/jbm.a.36640 ・Keiko Kudoh, Naoyuki Fukuda, Shohei Kasugai, Noriko Tachikawa, Kiyoshi Koyano, Yasuyuki Matsushita, Yoichiro Ogino, Kunio Ishikawa, Youji Miyamoto 　Maxillary sinus floor augmentation using low-crystalline carbonate apatite granules with simultaneous implant installation: First-in-human clinical trial 　Journal of Oral and Maxillofacial Surgery, 77(5), 985.e1-985.e11, 2019. 　doi: 10.1016/j.joms.2018.11.026 ・Takayuki Nakagawa, Naoyuki Fukuda, Shohei Kasugai, Noriko Tachikawa, Kiyoshi Koyano, Yasuyuki Matsushita, Masanori Sasaki, Kunio Ishikawa, Youji Miyamoto 　Application of low crystalline carbonate apatite granules in two-stage sinus floor augmentation: a prospective clinical trial and histomorphometric evaluation 　Journal of Periodontal & Implant Science, 49 (6), 382-396, 2019. 　doi: 10.5051/jpis.2019.49.6.382
	【2018】
	Back to top ・Yuki Sugiura, Melvin L. Munar, Kanji Tsuru, Kunio Ishikawa 　Fabrication of octacalcium phosphate foam through phase conversion and its histological evaluation 　Materials Letters, 212, 28-31, 2018. 　doi: 10.1016/j.matlet.2017.10.051 ・Kunio Ishikawa, Tansza Setiana Putri, Akira Tsuchiya, Keisuke Tanaka, Kanji Tsuru 　Fabrication of interconnected porous β-tricalcium phosphate (β-TCP) based on a setting reaction of β-TCP granules with HNO₃ followed by heat treatment 　Journal of Biomedical Materials Research: Part A. 106(3), 797-804, 2018. 　doi: 10.1002/jbm.a.36285 ・Toshiyuki Suge, Shingo Shibata, Kunio Ishikawa, Takashi Matsuo 　Fluoride activity of antibacterial ammonium hexafluorosilicate solution for the prevention of dentin caries 　American Journal of Dentistry. 31, 103-106, 2018. 　https://europepmc.org/article/med/29630795 ・Sunarso, Akira Tsuchiya, Naoyuki Fukuda, Riki Toita, Kanji Tsuru, Kunio Ishikawa 　Effect of micro-roughening of poly(ether ether ketone) on bone marrow derived stem cell and macrophage responses, and osseointegration 　Journal of Biomaterials Science: Polymer Edition, 29(12), 1375-1388, 2018. 　doi: 10.1080/09205063.2018.1461448 ・Kenji Fujisawa, Kazuya Akita, Naoyuki Fukuda, Go Ohe, Kanji Tsuru, Kunio Ishikawa, Youji Miyamoto 　Compositional and histological comparison of carbonate apatite fabricated by dissolution-precipitation reaction and Bio-Oss® 　Journal of Materials Science: Materials in Medicine, 29, 121, 2018. 　doi: 10.1007/s10856-018-6129-2 ・Yuki Sugiura, Kunio Ishikawa 　Effect of Ca and PO4 on compositional conversion from dicalcium hydrogen phosphate dihydrate blocks to octacalcium phosphate blocks 　Crystals, 8(5), 222, 2018. 　doi: 10.3390/cryst8050222 ・Garima Tripath, Yuki Sugiura, Aivaras Kareiva, Edita Garskaite, Kanji Tsuru, Kunio Ishikawa 　Feasibility evaluation of low-crystallinity β-tricalcium phosphate blocks as a bone substitute fabricated by a dissolution–precipitation reaction from α-tricalcium phosphate blocks 　Journal of Biomaterials Applications, 33(2), 259-270, 2018. 　doi: 10.1177/0885328218788255 ・Garima Tripathi, Yuki Sugiura, Kunio Ishikawa, Kanji Tsuru 　In vivo stability evaluation of Mg substituted low crystallinity β-tricalcium phosphate blocks fabricated through dissolution–precipitation reaction for fast bone regeneration 　Biomedical Materials, 13(6), 065002, 2018. 　doi: 10.1088/1748-605X/aad385 ・Masako Fujioka-Kobayashia, Kanji Tsuru, Hirokazu Nagai, Kenji Fujisawa, Takaharu Kudou, Go Ohe, Kunio Ishikawa, Youji Miyamoto 　Fabrication and evaluation of carbonate apatite-coated calcium carbonate bone substitutes for bone tissue engineering 　Journal of Tissue Engineering and Regenerative Medicine, 12(10), 2077-2087, 2018. 　doi: 10.1002/term.2742 ・Akira Tsuchiya, Marino Sato, Ichiro Takahashi, Kunio Ishikawa 　Fabrication of apatite-coated gypsum granules and histological evaluation using rabbits 　Ceramics International, 44(16), 20330-20336, 2018. 　doi: 10.1016/j.ceramint.2018.08.021 ・Yuki Sugiura, Kunio Ishikawa 　Fabrication of carbonate apatite blocks from octacalcium phosphate blocks through different phase conversion mode depending on carbonate concentration 　Journal of Solid State Chemistry, 261, 85-91, 2018. 　doi: 10.1016/j.ceramint.2018.08.021 ・Arief Cahyanto, Kanji Tsuru, Kunio Ishikawa 　Effect of setting atmosphere on apatite cement resorption: An in vitro and in vivo study 　Journal of the Mechanical Behavior of Biomedical Materials, 88, 463-469, 2018. 　doi: 10.1016/j.jmbbm.2018.08.021 ・Yuki Sugiura, Melvin L Munar, Kunio Ishikawa 　Fabrication of octacalcium phosphate block through a dissolution-precipitation reaction using a calcium sulphate hemihydrate block as a precursor 　Journal of Materials Science: Materials in Medicine, 29(10):151-158, 2018. 　doi: 10.1007/s10856-018-6162-1 ・Rui Shi, Yuki Sugiura, Kanji Tsuru, Kunio Ishikawa 　Fabrication of calcite-coated rough-surface titanium using calcium nitrate 　Surface and Coatings Technology, 356, 72-79, 2018. 　doi: 10.1016/j.surfcoat.2018.09.050 ・Eddy, Akira Tsuchiya, Kanji Tsuru, Kunio Ishikawa 　Fabrication of self-setting β-TCP granular cement using β-TCP granules and sodium hydrogen sulfate solution 　Journal of Biomaterials Applications, 33(5), 630-636, 2018. 　doi: 10.1177/0885328218808015 ・Kunio Ishikawa, Youji Miyamoto, Akira Tsuchiya, Koichiro Hayashi, Kanji Tsuru, Go Ohe 　Physical and histological comparison of hydroxyapatite, carbonate apatite, and β-tricalcium phosphate bone substitutes 　Materials, 11(10), 1993, 2018. 　doi: 10.3390/ma11101993 ・Naoyuki Fukuda, Masayuki Kanazawa, Kanji Tsuru, Akira Tsuchiya, Sunarso, Riki Toita, Yoshihide Mori, Yasuharu Nakashima, Kunio Ishikawa 　Synergistic effect of surface phosphorylation and micro-roughness on enhanced osseointegration ability of poly(ether ether ketone) in the rabbit tibia 　Scientific Reports, 8(1), 16887, 2018. 　doi: 10.1038/s41598-018-35313-7 ・Naoyuki Fukuda, Kanji Tsuru, Yoshihide Mori, Kunio Ishikawa 　Fabrication of self-setting β-tricalcium phosphate granular cement 　Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 106, 800-807, 2018. 　doi: 10.1002/jbm.b.33891
	【2017】
	Back to top ・Kunio Ishikawa, Giichiro Kawachi, Kanji Tsuru, Ayami Yoshimoto 　Fabrication of calcite blocks from gypsum blocks by compositional transformation based on dissolution–precipitation reactions in sodium carbonate solution 　Materials Science and Engineering C, 51, 389–393, 2017. 　doi: 10.1016/j.msec.2016.11.093 ・Khairul Anuar Shariff, Kanji Tsuru, Kunio Ishikawa 　Fabrication of dicalcium phosphate dihydrate-coated β-TCP granules and evaluation of their osteoconductivity using experimental rats 　Materials Science and Engineering C, 75, 1411-1419, 2017. 　doi: 10.1016/j.msec.2017.03.004 ・Naoyuki Fukuda, Kanji Tsuru, Yoshihide Mori, Kunio Ishikawa 　Effect of citric acid on setting reaction and tissue response to β-TCP granular cement 　Biomedical Materials, 12(1), 15027, 2017. 　doi: 10.3390/ma10040374 ・Masayuki Kanazawa, Kanji Tsuru, Naoyuki Fukuda, Yuta Sakemi, Yasuharu Nakashima, Kunio Ishikawa 　Evaluation of carbonate apatite blocks fabricated from dicalcium phosphate dihydrate blocks for reconstruction of rabbit femoral and tibial defects 　Journal of Materials Science: Materials in Medicine, 28, 85, 2017. 　doi: 10.1007/s10856-017-5896-5 ・Tya Indah Arifta, Melvin L. Munar, Kanji Tsuru, Kunio Ishikawa 　Fabrication of interconnected porous calcium-deficient hydroxyapatite using the setting reaction of α tricalcium phosphate spherical granules 　Ceramics International, 43,11149-11155, 2017. 　doi: 10.1016/j.ceramint.2017.05.162 ・Inga Grigoraviciute-Puroniene, Kanji Tsuru, Edita Garškaite, Živilė Stankevičiũté, Aldona Beganskienė, Kunio Ishikawa, Aivaras Kareiva 　A novel wet polymeric precipitation synthesis method for monophasic β-TCP 　Advanced Powder Technology, 28, 2325-2331, 2017. 　doi: 10.1016/j.apt.2017.06.014 ・Yuki Sugiura, Kanji Tsuru, Kunio Ishikawa 　Fabrication of arbitrarily shaped carbonate apatite foam based on the interlocking process of dicalcium hydrogen phosphate dihydrate 　Journal of Materials Science: Materials in Medicine, 28, 122, 2017. 　doi: 10.1007/s10856-017-5937-0
	【2016】
	Back to top ・Shariff Khairul Anuar, Kanji Tsuru, Kunio Ishikawa 　Fabrication of interconnected pore forming α-tricalcium phosphate foam granules cement 　Journal of Biomaterials Applications. 30(6), 838-45, 2016. 　doi: 10.1177/0885328215601939 ・Xingling Shi, Lingli Xu, Le Thi Bang, Guanghong Zhou, Chuanbo Zheng, Kanji Tsuru, Kunio Ishikawa 　Partial oxidation of TiN coating by hydrothermal treatment and ozone treatment to improve its osteoconductivity 　Materials Science and Engineering: C, 59, 542-548, 2016. 　doi: 10.1016/j.msec.2015.10.024 ・Yuki Sugiura, Kanji Tsuru, Kunio Ishikawa 　Fabrication of carbonate apatite foam based on the setting reaction of α-tricalcium phosphate foam granules 　Ceramics International, 42, 204-210, 2016. 　doi: 10.1016/j.ceramint.2015.08.081 ・Siti Noorzidah Mohd Sabri, Synzana Abu Bakar, Abdul Yazid Abdul Manaf, Siti Frahana Hisham, Mohd Azmirrudin Ahmed, Kalitheertha Jamuna-Thevi, Kartini Norrsal, Hairul Anuar Shafiff, Kunio Ishikawa 　Phase transformation of biphasic granules of gypsum and carbonated apatite at low temperatures 　Advanced Materials Research, 1133, 50-54, 2016. 　doi: 10.4028/www.scientific.net/AMR.1133.50 ・Noriko Koga, Kunio Ishikawa, Kanji Tsuru, Ichiro Takahashi 　Effects of acidic calcium phosphate concentration on mechanical strength of porous calcite fabricated by bridging with dicalcium phosphate dihydrate 　Ceramics International, 42(7), 7912-7917, 2016. 　doi: 10.1016/j.ceramint.2015.12.017 ・Masaaki Takechi, Yoshiaki Ninomiya, Kouji Ohta, Misato Tada, Kazuki Sasaki, Rahman Mohammad Zeshaan, Akira Ohta, Kanji Tsuru, Kunio Ishikawa 　Effects of apatite cement containing atelocollagen on attachment to, and proliferation and differentiation of MC3T3-E1 osteoblastic cells 　Materials, 9(4), 283, 2016. 　doi: 10.3390/ma9040283 ・Kunio Ishikawa, Noriko Koga, Kanji Tsuru, Ichiro Takahashi 　Fabrication of interconnected porous calcite by bridging calcite granules with dicalcium phosphate dihydrate and their histological evaluation 　Journal of Biomedical Materials Research: Part A, 104(3), 652-658, 2016. 　doi: 10.1002/jbm.a.35604 ・Yuki Sugiura, Kanji Tsuru and Kunio Ishikawa 　Fabrication of carbonate apatite pseudomorph from highly soluble acidic calcium phosphate salts through carbonation 　Journal of the Ceramic Society of Japan, 124(8), 827-832, 2016. 　doi: 10.2109/jcersj2.16046 ・Sunarso, Riki Toita, Kanji Tsuru and Kunio Ishikawa 　Immobilization of calcium and phosphate ions improves the osteoconductivity of titanium implants 　Materials Science and Engineering C, 68, 291-298, 2016. 　doi: 10.1016/j.msec.2016.05.090 ・Sunarso, Riki Toita, Kanji Tsuru, Kunio Ishikawa 　A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses 　Journal of Materials Science: Materials in Medicine, 27(8):127, 2016. 　doi: 10.1007/s10856-016-5741-2 ・Kanae Hara, Kenji Fujisawa, Hirokazu Nagai, Natsumi Takamaru, Go Ohe, Kanji Tsuru, Kunio Ishikawa, Youji Minamoto 　Fabrication and physical evaluation of gelatin-coated carbonate apatite foam 　Materials, 9(9), 711, 2016. 　doi: 10.3990/ma9090711 ・Yukie Shibata, Yoshihisa Yamashita, Kanji Tsuru, Kazuhiko Ishihara, Kyoko Fukazawa, Kunio Ishikawa 　Preventive effects of a phospholipid polymer coating on PMMA on biofilm formation by oral streptococci 　Applied Surface Science, 390, 602–607, 2016. 　doi: 10.1016/j.apsusc.2016.08.108
	【2015】
	Back to top ・Ahmed Nafis Rashid, Kanji Tsuru, Kunio Ishikawa 　Effect of calcium-ozone treatment on chemical and biological properties of polyethylene terephthalate 　Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 103(4), 853-60, 2015. 　doi: 10.1002/jbm.b.33260 ・Kunio Ishikawa, Nguyen Xuan Thanh Tram, Kanji Tsuru, Riki Toita 　Fabrication of porous calcite using chopped nylon fiber and its evaluation using rats 　Journal of Materials Science: Materials in Medicine, 26(2), 94-101, 2015. 　doi: 10.1007/s10856-015-5432-4 ・Hirokazu Nagai, Masako Fujioka-Kobayashi, Kenji Fujisawa, Go Ohe, Natsumi Takamaru, Kanae Hara, Daisuke Uchida, Tetsuya Tamatani, Kunio Ishikawa, Youji Miyamoto 　Effects of low crystalline carbonate apatite on proliferation and osteoblastic differentiation of human bone marrow cells 　Journal of Materials Science: Materials in Medicine, 26(2), 99-107, 2015. 　doi: 10.1007/s10856-015-5431-5 ・Noriko Koga, Kanji Tsuru, Ichiro Takahashi, Kunio Ishikawa 　Effects of humidity on calcite block fabrication using calcium hydroxide compact 　Ceramics International, 41(8), 9482-9487, 2015. 　doi: 10.1016/j.ceramint.2015.04.005 ・Arief Cahyanto, Michito Maruta, Kanji Tsuru, Shigeki Matsuya, Kunio Ishikawa 　Fabrication of bone cement that fully transforms to carbonate apatite 　Dental Materials Journal, 34(3), 394-401, 2015. 　doi: 10.4012/dmj.2014-328 ・Taro Nikaido, Kanji Tsuru, Melvin Munar, Michito Maruta, Shigeki Matsuya, Seiji Nakamura, Kunio Ishikawa 　Fabrication of β-TCP foam: effects of magnesium oxide as phase stabilizer on its properties 　Ceramics International, 41, 14245-14250, 2015. 　doi: 10.1016/j.ceramint.2015.07.053 ・Alireza Valanezhad, Kanji Tsuru, Kunio Ishikawa 　Fabrication of strongly attached hydroxyapatite coating on titanium by hydrothermal treatment of Ti-Zn-PO₄ coated titanium in CaCl₂ solution 　Journal of Materials Science: Materials in Medicine, 26(7), 5548-5557, 2015. 　doi: 10.1007/s10856-015-5548-6 ・Pham Trung Kien, Kunio Ishikawa, Kanji Tsuru 　Setting reaction of α-TCP spheres and an acidic calcium phosphate solution for the fabrication of fully interconnected macroporous calcium phosphate 　Ceramics International, 41(10), 13525-13531, 2015. 　doi: 10.1016/j.ceramint.2015.07.146 ・Yasunori Ayukawa, Yumiko Suzuki, Kiyoshi Koyano, Kunio Ishikawa, Kanji Tsuru 　Histological comparison in rats between carbonate apatite fabricated from gypsum and sintered hydroxyapatite on bone remodeling 　BioMed Research International, 2015, 579541-1-7, 2015. 　doi: 10.1155/2015/579541 ・Kanji Tsuru, Ruslin, Shigeki Matsuya, Kunio Ishikawa 　Effects of the method of apatite seed crystals addition on setting reaction of α-tricalcium phosphate based apatite cement 　Journal of Materials Science: Materials in Medicine, 26, 244, 2015. 　doi: 10.1007/s10856-015-5570-8 ・Xingling Shi, Lingli Xu, Melvin L. Munar, Kunio Ishikawa 　Hydrothermal treatment for TiN as abrasion resistant dental implant coating and its fibroblast response 　Materials Science and Engineering: C, 49, 1-6, 2015. 　doi: 10.1016/j.msec.2014.12.059 ・Riki Toita, Sunarso, Ahmed Nafis Rashid, Kanji Tsuru, Kunio Ishikawa 　Modulation of the osteoconductive property and immune response of poly(ether ether ketone) by modification with calcium ions 　Journal of Materials Chemistry B, 3(44), 8738-8746, 2015. 　doi: 10.1039/C5TB01679G